SEPTEMBER 2026


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A Chain of Hope

Kristi Noone’s Personal Passion for Kidney Donation

We are honored to share the story of Kristi Noone, a Westwood resident who has donated a kidney to save someone’s life, setting up an incredible human chain of donations across the country. Kristi’s brother is in need of a kidney donation, so her passion is palpable and we are proud to raise the profile of an important issue.

By Diana Bezdedeanu
Feature Photos By: Rick Bern

 

In the winter of 2015, while historic blizzards buried Westwood with record-breaking snowfall, Kristi Noone was cozy inside her home, recovering from surgery. She had just donated a kidney to a stranger in New York, a selfless choice similar to one that allowed her brother, Jeff, to receive a life-saving kidney from a stranger in Connecticut. What neither sibling anticipated was that her act of sisterly love would be part of a momentous domino effect: 70 patients across 25 hospitals in what remains the longest kidney transplant chain to date.
 

“Jeff and I had our surgeries on the same day,” Kristi said. “Even though I wasn’t a direct match to Jeff, I was thrilled I could help him and someone else.”
 

Resilience has defined much of Jeff’s life: a childhood cancer survivor, his journey with kidney struggles stretches back nearly twenty years. He channels that experience into his job at Dana-Farber Cancer Institute, where he works in a research lab, focused on Multiple Myeloma. Away from work, Jeff’s world revolves around his close-knit family. Though he’s a loyal Boston sports fan, his favorite games to watch are his nephews’, where he could frequently be found in the stands, loudly cheering them on.
 

“When he was about 30, Jeff began having symptoms of kidney disease,” Kristi said. “We’re not really sure of the exact cause, but we believe it could be linked to effects of chemotherapy he received as a child. He was headed for end-stage renal disease, which advanced over the course of seven years before he needed to start dialysis and begin the process of becoming eligible for a transplant.”
 

Waiting for a deceased donor organ on the national registry in New England can take up to six very long and trying years. Knowing time was of the essence, Jeff’s inner circle stepped forward immediately.
 

“The list is long,” Kristi admitted. “Our family members and friends began testing to donate to him, but everyone who tested was either medically disqualified or not a match.”
 

Beyond avoiding years on a waitlist, receiving an organ from a living donor offers critical medical advantages over a deceased donor kidney. Living donor kidneys typically begin functioning immediately upon transplantation, whereas organs from deceased donors can take days or weeks to resume normal function, often requiring temporary dialysis in the interim. On top of that, living donor kidneys carry lower rates of rejection and last significantly longer on average, typically 15 to 20 years or more, compared to 10 to 12 years for deceased donor organs. Most importantly, living donation also allows the procedure to be scheduled in advance when both the donor and recipient are in optimal health, rather than relying on an emergency call in the middle of the night.
 

After understanding all of this information, the family discovered the National Kidney Registry (NKR), an organization that matches donors and recipients nationwide through paired exchanges.
 

“Qualified donors didn’t need to be a direct match,” Kristi explained. “The NKR matches donor and recipient pairs with other donors and recipients in their database, which is nationwide. So that was a great option for us. The more who enter the database, the better, because it’s more likely to lead to a match.”
 

Then came the moment they had been praying for.
 

“In December 2014, I got the call that they found a match for me and a match for Jeff.”
 

Kristi vividly recalled the intense wave of emotions that hit her when the hospital called.
 

“It was nerves, excitement, relief, a weird mix of everything,” Kristi said. “However, they assured me that while it’s major surgery, it’s a routine procedure and we were going to be okay.”
 

Just a month later, Kristi and Jeff underwent their respective transplant procedures. From there, the entire chain unfolded seamlessly over just a few short months, connecting transplant patients all across the country.
 
Learn more about the cause and how you can help by CLICKING HERE
 
“It started in the beginning of January and went through the end of March,” Kristi said. “ABC’s Nightline did a story about it. Locally, WCVB aired a story on the same night as the national story. The Nightline story followed the last segment of the chain in real time as it was happening. At one point they showed a map with a little line binging across the country, going all over the place, connecting all 35 transplants. They got everyone the best match possible, even if it meant flying it.”
 

For nine years, that donated kidney allowed Jeff to live a full, energetic life. For Kristi, adjusting to life as a living donor proved remarkably effortless once she healed.
 

“In about two to three weeks, I had recovered surgically,” Kristi said. “Adjusting to one kidney took a couple months, but then I felt great. I don’t even think about it most days. I don’t feel any different now than I did with two kidneys. I ran the Falmouth Road Race seven months post-donation, three times total for the National Kidney Foundation, and I was really proud of myself for crossing that finish line so soon after donating. I don’t have any restrictions as far as diet, exercise, or activities. I don’t have to take any medications. I just have to take care of myself and everything in moderation, just like everyone should do.”
 

Kristi’s quick recovery and active lifestyle caught the attention of Rock 1 Kidney, a nonprofit dedicated to inspiring courage in potential living donors by sharing stories of everyday people who are “rocking one kidney” post-donation. Kristi was featured in their campaign shortly after running Falmouth.
 

Unfortunately, two years ago, Jeff’s transplanted kidney began to fail. A transplant, after all, is a life-extending treatment rather than a permanent cure, and the failure forced Jeff back onto dialysis while restarting the grueling evaluation process. This time around, finding a compatible match is far more complicated.
 

“He is on the list, but this time he’s more difficult to match,” Kristi shared. “He’s been in the NKR database for over a year, with no luck. He has antibodies from the first kidney transplant and from blood transfusions he’s had from the cancer.”
 

Navigating daily life on dialysis while continuing to work full-time demands extraordinary discipline and endurance.
 

“He does dialysis three days a week at five in the morning so that he’s done by nine. Dialysis is exhausting. After dialysis, he starts his work day. He’s the strongest person I know.”
 

Seeing Jeff face this daunting ordeal a second time was devastating for the family, but Kristi quickly stepped up to take action as his primary health advocate.
 

“Initially, our family was devastated because we know how stressful it is to be waiting for a kidney, how hard it is to live with end-stage renal disease, and how horrible dialysis is,” Kristi confessed. “But then we had to snap into advocate mode. I can’t donate again. I absolutely would if I could. So now I take action as his advocate, helping manage the search, getting the word out through our Facebook page and our website.”

 
In doing so, Kristi wants potential donors to know that they do not need to be a direct blood match for Jeff to save his life. Through modern paired exchange and the NKR Voucher Program, anyone who steps forward to donate on Jeff’s behalf would enable him to receive a voucher and be prioritized in the NKR database.
 

“Although a direct match would be ideal, you don’t have to be a direct match to help him,” Kristi explained. “You can do what we did with the paired exchange. And now they took it one step further with the voucher program, so donors can donate at any NKR partner hospital nationwide at their convenience and give a voucher to Jeff. Donors can even designate backup voucher holders. Potential donors are thoroughly tested to ensure donation is safe, everything is confidential, you have a separate team of doctors, and you can back out at any time.”
 

As she works to spread the word, Kristi draws strength from her local community. Having lived in Westwood for nearly 30 years and raised two Westwood High School graduates here, she feels a deep affection for her neighbors and community.

 
“It’s such a caring and supportive community,” Kristi said of the town. “It feels very natural and comfortable for me to turn to my neighbors for support, but it’s also pretty humbling at the same time. In 2015, after my surgery, people poured out of the woodwork with meals and helped with the kids.”
 

Now, she is calling on that community once again.
 

“Besides considering being tested, I would love to ask anyone reading this to help by following our Facebook page, sharing our website, or reaching out if they have a large network, social media following, or a business willing to post a flyer,” Kristi urged. “Donors can be anywhere in the country, so we don’t have to keep it local. Just sharing Jeff’s story increases the chances of reaching the person who could save his life.”
 

Through every twist and turn of this journey, Kristi remains determined to bring her brother back to full health.
 

“We know it’s possible because we did it once, so we’ve got to do it again,” Kristi concluded. “He can’t stay on dialysis forever. A kidney transplant would give Jeff his life back; the strength and freedom to travel, go to concerts, and make more memories with his girlfriend, friends, and family.”
 

To learn more about kidney donation, get confidential screening information, or help Jeff’s search, visit Jeff’s website at www.nkr.org/waf939, the Facebook page Let’s Find Jeff a Kidney, or reach out to AdvocateForJeff@gmail.com.
 

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Photos By Rick Bern Photography

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